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Sunitinib, MedChemExpress

Artikelnummer. 16490956
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Artikelnummer. Mængde
16490956 200 mg
16481546 500 mg
16464806 100 mg
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Artikelnummer. 16490956 Leverandør Medchem Express Leverandørnr. HY10255A

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Beskrivelse

MedChemExpress Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Tekniske data

Kemisk navn eller materiale Sunitinib
CAS 557795-19-4
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C22H27FN4O2
Mængde 200 mg
Synonym SU 11248
Opløselighedsinformation DMSO : 20.83 mg/mL (52.27 mM; ultrasonic and warming and heat to 80°C)
SMIL O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C
Molekylvægt (g/mol) 398.47
Formel vægt 398.47
Procent renhed 98.0%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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