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Sulindac, MedChemExpress

Artikelnummer. 16478056
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500 mg
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16478056 100 mg
16441996 500 mg
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Artikelnummer. 16478056 Leverandør Medchem Express Leverandørnr. HYB0008

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Beskrivelse

MedChemExpress Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent.

Sulindac is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthritis of the spine, gouty arthritis. Sulindac, as an immunomodulatory agent, can downregulate PD-L1 through the blockade of NF-κB signaling and modulates the response of pMMR colorectal cancer (CRC) to anti-PD-L1 immunotherapy, inhibits the development and progression of colorectal cancer CRC. Sulindac also inhibits TGF-β1- induced epithelial-mesenchymal transition (EMT) and suppresses lung cancer cell migration and invasion via downregulation of SIRT1.

Tekniske data

Kemisk navn eller materiale Sulindac
CAS 38194-50-2
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C20H17FO3S
Mængde 100 mg
Synonym MK-231
Opløselighedsinformation DMSO : 100 mg/mL (280.58 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMIL O=C(CC(C1=C2C=CC(F)=C1)=C(/C2=C/C3=CC=C(C=C3)S(C)=O)C)O
Molekylvægt (g/mol) 356.41
Formel vægt 356.41
Procent renhed 99.34%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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