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Selumetinib, MedChemExpress

Product Code. 16491916
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16491916 500 mg -
16474007 50 mg 50mg
16471316 200 mg -
16467856 100 mg -
16401939 1 g 1g
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Product Code. 16491916 Supplier Medchem Express Supplier No. HY50706

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Description

MedChemExpress Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Specifications

Kemisk navn eller materiale Selumetinib
CAS 606143-52-6
Farve White
Renhedsgrad noter Research
Molekylær formel C17H15BrClFN4O3
Mængde 500 mg
Synonym AZD6244 ARRY-142886
Opløselighedsinformation DMSO : 10 mg/mL (21.85 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL O=C(C1=C(C(F)=C2N=CN(C2=C1)C)NC3=CC=C(C=C3Cl)Br)NOCCO
Molekylvægt (g/mol) 457.68
Formel vægt 457.68
Procent renhed 98.01%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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