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Rucaparib phosphate, MedChemExpress

Artikelnummer. 16490996
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Artikelnummer. 16490996 Leverandør Medchem Express Leverandørnr. HY10617

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Beskrivelse

MedChemExpress Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research.

Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research.

Tekniske data

Kemisk navn eller materiale Rucaparib phosphate
CAS 459868-92-9
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C19H21FN3O5P
Mængde 200 mg
Synonym AG-014699 phosphatePF-01367338 phosphate
Opløselighedsinformation DMSO : ≥ 33 mg/mL (78.32 mM) ∣H2O : 5 mg/mL (11.87 mM; ultrasonic and warming and heat to 60°C)
SMIL O=P(O)(O)O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1
Molekylvægt (g/mol) 421.36
Formel vægt 421.36
Procent renhed 98.77%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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