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  8. RU-SKI 43 hydrochloride, MedChemExpress

RU-SKI 43 hydrochloride, MedChemExpress

Artikelnummer. 16443537
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16443537 50 mg
16417518 10 mg
16409997 5 mg
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Artikelnummer. 16443537 Leverandør Medchem Express Leverandørnr. HY18366A

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Beskrivelse

MedChemExpress RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity.

RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity.

Tekniske data

Kemisk navn eller materiale RU-SKI 43 hydrochloride
CAS 1782573-67-4
Farve White
Renhedsgrad noter Research
Molekylær formel C22H31ClN2O2S
Mængde 50 mg
Opløselighedsinformation DMSO : ≥ 51 mg/mL (120.56 mM) ∣H2O : 2.5 mg/mL (5.91 mM; Need ultrasonic)
SMIL [H]Cl.O=C(CNCC(C)CC)N1CCC2=C(C=CS2)C1COC3=CC=CC(C)=C3
Molekylvægt (g/mol) 423.01
Formel vægt 423.01
Procent renhed 98.54%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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