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Ro 67-7476, MedChemExpress

Artikelnummer. 16444306
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Artikelnummer. 16444306 Leverandør Medchem Express Leverandørnr. HY100403

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Descrizione

MedChemExpress Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).

Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).

Specifica

Kemisk navn eller materiale Ro 67-7476
CAS 298690-60-5
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C17H18FNO2S
Mængde 100 mg
Opløselighedsinformation DMSO : ≥ 40 mg/mL (125.24 mM)
SMIL O=S(N1[C@H](C2=CC=C(F)C=C2)CCC1)(C3=CC=C(C)C=C3)=O
Molekylvægt (g/mol) 319.39
Formel vægt 319.39
Procent renhed 98.54%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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