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Rigosertib, MedChemExpress

Artikelnummer. 16484938
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Artikelnummer. 16484938 Leverandør Medchem Express Leverandørnr. HY12037A

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Beskrivelse

MedChemExpress Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

Tekniske data

Kemisk navn eller materiale Rigosertib
CAS 592542-59-1
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C21H25NO8S
Mængde 10 mg
Synonym ON-01910
Opløselighedsinformation DMSO : 75 mg/mL (166.12 mM; Need ultrasonic)
SMIL COC1=CC=C(C=C1NCC(O)=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)]
Molekylvægt (g/mol) 451.49
Formel vægt 451.49
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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