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RG-12525, MedChemExpress

Artikelnummer. 16496217
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10 mg
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Artikelnummer. Mængde
16496217 5 mg
16443498 10 mg
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Artikelnummer. 16496217 Leverandør Medchem Express Leverandørnr. HY101676

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Beskrivelse

MedChemExpress RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 μM.

RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively

Tekniske data

Kemisk navn eller materiale RG-12525
CAS 120128-20-3
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C25H21N5O2
Mængde 5 mg
Synonym NID 525
Opløselighedsinformation DMSO : 25 mg/mL (59.04 mM; Need ultrasonic)
SMIL C1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1
Molekylvægt (g/mol) 423.47
Formel vægt 423.47
Procent renhed 98.39%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-sugar/lipid metabolism
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Research purposes only

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