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R406 free base, MedChemExpress

Artikelnummer. 16494398
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16494398 10 mg
16490717 50 mg
16455296 100 mg
16407127 5 mg
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Artikelnummer. 16494398 Leverandør Medchem Express Leverandørnr. HY11108

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Beskrivelse

MedChemExpress R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Tekniske data

Kemisk navn eller materiale R406 free base
CAS 841290-80-0
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C22H23FN6O5
Mængde 10 mg
Opløselighedsinformation DMSO : ≥ 10 mg/mL (21.26 mM)
SMIL COC1=CC(NC2=NC(NC3=NC(N4)=C(C=C3)OC(C)(C)C4=O)=C(C=N2)F)=CC(OC)=C1OC
Molekylvægt (g/mol) 470.45
Formel vægt 470.45
Procent renhed 98.15%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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