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Thermo Scientific™ (R,R)-Chloramphenicol, 98%

(R,R)-Chloramphenicol, CAS # 56-75-7, also known as chloromycetin, is a compound with broad-spectrum antibiotic and bacteriostatic activities.

352.24 DKK - 1119.42 DKK

Kemiske identifikatorer

CAS 56-75-7
Molekylær formel C11H12Cl2N2O5
Molekylvægt (g/mol) 323.126
MDL nummer MFCD00078159
InChI nøgle WIIZWVCIJKGZOK-RKDXNWHRSA-N
PubChem CID 5959
ChEBI CHEBI:17698
IUPAC navn 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMIL C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
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Produkter 2
Produktkode Brand Mængde Pris Antal & tilgængelighed  
Produktkode Brand Mængde Pris Antal & tilgængelighed  
11445786
Dokumentvisning
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Thermo Scientific™
B20841.14 		25g
352.24 DKK
25g
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11455786
Dokumentvisning
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Thermo Scientific™
B20841.22 		100g
1119.42 DKK
100g
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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

  • (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
  • It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation

Application

  • (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
  • This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
  • In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
Tekniske data

Kemiske identifikatorer

56-75-7
323.126
WIIZWVCIJKGZOK-RKDXNWHRSA-N
CHEBI:17698
C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
C11H12Cl2N2O5
MFCD00078159
5959
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Tekniske data

Chloramphenicol
0.99
MFCD00078159
14,2077
WIIZWVCIJKGZOK-RKDXNWHRSA-N
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
5959
323.14
56-75-7
C11H12Cl2N2O5
2225532
Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water.
C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
323.126
CHEBI:17698
≥99%
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Sikkerhed og håndtering

Sikkerhed og håndtering

GHS H Statement
H350-H361

P201-P202-P281-P308+P313-P501c

H350

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missing translation for 'tsca' : Yes

Produktidentifikator
  • (R,R)-Chloramphenicol

Signalord
  • Fare

Farekategori
  • Carcinogenicitet Kategori 1B

Faresætning
  • H350-Kan fremkalde kræft.

Sikkerhedssætning
  • P201-Indhent særlige anvisninger før brug.
  • P308+P313-VED eksponering eller mistanke om eksponering: Søg lægehjælp.

Supplerende oplysninger
  • MIXTURE LIST-Indeholder: Chloramphenicol

SDS
Dokumenter

Dokumenter

Produktcertifikater

RUO – Research Use Only

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