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Thermo Scientific™ (R,R)-Chloramphenicol, 98%

(R,R)-Chloramphenicol, CAS # 56-75-7, also known as chloromycetin, is a compound with broad-spectrum antibiotic and bacteriostatic activities.

Brand:  Thermo Scientific™ B20841.22


Mængde 100g

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Regulatorisk: Dette produkt falder ind under Lov om kemiske stoffer og produkter - lovbekendtgørelse nr. 1755 af 22. december 2006. Hvis det er relevant, skal kunden fremskaffe en licens før levering.

Produktkode 11455786

  • 1119.42 DKK / 100g

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

  • (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
  • It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation

Application

  • (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
  • This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
  • In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

56-75-7
323.126
WIIZWVCIJKGZOK-RKDXNWHRSA-N
5959
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
C11H12Cl2N2O5
MFCD00078159
Chloromycetin
CHEBI:17698
C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

Tekniske data

(R,R)-Chloramphenicol
Cream to White
0.99
MFCD00078159
14,2077
Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water.
C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
323.126
CHEBI:17698
≥99%
56-75-7
100g
C11H12Cl2N2O5
2225532
Chloromycetin
WIIZWVCIJKGZOK-RKDXNWHRSA-N
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
5959
323.14
Produktforslag

Produktforslag

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Sikkerhed og håndtering

Sikkerhed og håndtering

Produktidentifikator
  • (R,R)-Chloramphenicol

Signalord
  • Fare

Farekategori
  • Carcinogenicitet Kategori 1B

Faresætning
  • H350-Kan fremkalde kræft.

Sikkerhedssætning
  • P201-Indhent særlige anvisninger før brug.
  • P308+P313-VED eksponering eller mistanke om eksponering: Søg lægehjælp.

Supplerende oplysninger
  • MIXTURE LIST-Indeholder: Chloramphenicol

SDS
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Kampagner

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