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PTC299, MedChemExpress

Artikelnummer. 16497897
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Mængde:
5 mg
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Artikelnummer. Mængde
16497897 5 mg
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Artikelnummer. 16497897 Leverandør Medchem Express Leverandørnr. HY124593

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Beskrivelse

MedChemExpress PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.

PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.

Tekniske data

Kemisk navn eller materiale PTC299
CAS 1256565-36-2
Farve White
Renhedsgrad noter Research
Molekylær formel C25H20Cl2N2O3
Mængde 5 mg
Opløselighedsinformation DMSO : 50 mg/mL (106.99 mM; Need ultrasonic)
SMIL O=C(N([C@H]1C2=CC=C(OC)C=C2)CCC3=C1NC4=C3C=C(Cl)C=C4)OC5=CC=C(Cl)C=C5
Molekylvægt (g/mol) 467.34
Formel vægt 467.34
Procent renhed 98.24%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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