missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Kemikalier
  4. Organiske forbindelser
  5. Benzenoider
  6. Benzen og substituerede derivater
  7. Phenoxyforbindelser
  8. Prexasertib dihydrochloride, MedChemExpress

Prexasertib dihydrochloride, MedChemExpress

Artikelnummer. 16483497
Encompass_Preferred
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
5 mg
10 mg
25 mg
50 mg
100 mg
Pakningsstørrelse:
10mg
25mg
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde unitSize
16483497 50 mg -
16443596 25 mg 25mg
16437478 10 mg 10mg
16429957 5 mg -
16407446 100 mg -
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 16483497 Leverandør Medchem Express Leverandørnr. HY18174A

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

MedChemExpress Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity.

Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity.

Tekniske data

Kemisk navn eller materiale Prexasertib dihydrochloride
CAS 1234015-54-3
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C18H21Cl2N7O2
Mængde 50 mg
Synonym LY2606368 dihydrochloride
Opløselighedsinformation DMSO : 8 mg/mL (18.25 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.28 mM; ultrasonic and warming and heat to 80°C)
SMIL NCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2.[H]Cl.[H]Cl
Molekylvægt (g/mol) 438.31
Formel vægt 438.31
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
Vis mere Vis mindre

Research purposes only

Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.