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Tocris Bioscience™ Pifithrin-μ
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Artikelnummer. 18064332
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Mængde:
10 mg
50 mg
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Artikelnummer. Mængde
18064332 10 mg
18054112 50 mg
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Artikelnummer. 18064332 Leverandør Tocris Bioscience™ Leverandørnr. 2653/10

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Beskrivelse

Inhibitor of p53-mitochondrial binding

Pifithrin-μ inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. Displays no effect on the transactivational or cell cycle checkpoint control function of p53. Potentially increases reprogramming efficiency of human somatic cells to induced pluripotent stem cells (iPSCs) by silencing p53. Pifithrin-μ reduces cell death induced by γ-radiation in vitro and protects mice from doses of radiation that cause lethal hematopoietic syndrome. Selectively inhibits heat shock protein 70 (HSP70) activity.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 64984-31-2
Molekylær formel C8H7NO2S

Tekniske data

Kemisk navn eller materiale Pifithrin-μ
Mængde 10 mg
Formel vægt 181.21
Renhed >99%
Molekylvægt (g/mol) 181.209
Produkttitel
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