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PFI-2 hydrochloride, MedChemExpress

Artikelnummer. 16453567
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50 mg
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Artikelnummer. Mængde
16453567 50 mg
16437548 10 mg
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Artikelnummer. 16453567 Leverandør Medchem Express Leverandørnr. HY18627A

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Beskrivelse

MedChemExpress PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.

PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.

Tekniske data

Kemisk navn eller materiale PFI-2 hydrochloride
CAS 1627607-87-7
Farve White
Renhedsgrad noter Research
Molekylær formel C23H26ClF4N3O3S
Mængde 50 mg
Synonym (R)-PFI-2 hydrochloride
Opløselighedsinformation DMSO : ≥ 32 mg/mL (59.70 mM) ∣H2O : 5.56 mg/mL (10.37 mM; Need ultrasonic)
SMIL O=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O.[H]Cl
Molekylvægt (g/mol) 535.98
Formel vægt 535.98
Procent renhed 96.09%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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