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PCI 29732, MedChemExpress

Artikelnummer. 16467416
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16467416 100 mg
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Artikelnummer. 16467416 Leverandør Medchem Express Leverandørnr. HY18010

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Beskrivelse

MedChemExpress PCI 29732 is a potent, orally active, reversible BTK inhibitor with Kiapp values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.

PCI 29732 is a potent, orally active, reversible BTK inhibitor with Kiapp values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.

Tekniske data

Kemisk navn eller materiale PCI 29732
CAS 330786-25-9
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C22H21N5O
Mængde 100 mg
Opløselighedsinformation DMSO : ≥ 53 mg/mL (142.69 mM) ∣Ethanol : 10 mg/mL (26.92 mM; Need ultrasonic)
SMIL NC1=NC=NC2=C1C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN2C5CCCC5
Molekylvægt (g/mol) 371.44
Formel vægt 371.44
Procent renhed 99.86%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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