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Pamapimod, MedChemExpress

Artikelnummer. 16433948
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16433948 10 mg
16422926 25 mg
16416667 5 mg
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Artikelnummer. 16433948 Leverandør Medchem Express Leverandørnr. HY10405

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Beskrivelse

MedChemExpress Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Tekniske data

Kemisk navn eller materiale Pamapimod
CAS 449811-01-2
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C19H20F2N4O4
Mængde 10 mg
Synonym Ro4402257 R1503
Opløselighedsinformation DMSO : ≥ 34 mg/mL (83.67 mM)
SMIL O=C1C(OC2=CC=C(F)C=C2F)=CC3=CN=C(NC(CCO)CCO)N=C3N1C
Molekylvægt (g/mol) 406.38
Formel vægt 406.38
Procent renhed 99.92%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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