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NXT629, MedChemExpress

Artikelnummer. 16477547
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5mg
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Artikelnummer. Mængde unitSize
16477547 5 mg 5mg
16471067 50 mg -
16415606 100 mg -
16414808 10 mg -
16403256 25 mg 25mg
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Artikelnummer. 16477547 Leverandør Medchem Express Leverandørnr. HY114263

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Beskrivelse

MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

Tekniske data

Kemisk navn eller materiale NXT629
CAS 1454925-59-7
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C35H39N5O3S
Mængde 5 mg
Opløselighedsinformation DMSO : 125 mg/mL (204.99 mM; Need ultrasonic)
SMIL O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
Molekylvægt (g/mol) 609.78
Formel vægt 609.78
Procent renhed 99.2%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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