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NPS-2143 hydrochloride, MedChemExpress

Artikelnummer. 16499956
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16499956 50 mg
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16426247 5 mg
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Artikelnummer. 16499956 Leverandør Medchem Express Leverandørnr. HY10171

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Beskrivelse

MedChemExpress NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.

NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.

Tekniske data

Kemisk navn eller materiale NPS-2143 hydrochloride
CAS 324523-20-8
Farve White
Renhedsgrad noter Research
Molekylær formel C24H26Cl2N2O2
Mængde 50 mg
Synonym SB-262470A hydrochloride
Opløselighedsinformation DMSO : ≥ 100 mg/mL (224.53 mM) ∣H2O : 1.85 mg/mL (4.15 mM; ultrasonic and warming and heat to 60°C)
SMIL N#CC1=C(OC[C@@H](CNC(C)(C)CC2=CC=C3C=CC=CC3=C2)O)C=CC=C1Cl.[H]Cl
Molekylvægt (g/mol) 445.38
Formel vægt 445.38
Procent renhed 99.94%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-protein/nucleotide metabolism
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Research purposes only

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