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Nevanimibe hydrochloride, MedChemExpress

Artikelnummer. 16499556
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16499556 50 mg
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16434306 100 mg
16405737 5 mg
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Artikelnummer. 16499556 Leverandør Medchem Express Leverandørnr. HY100399A

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Beskrivelse

MedChemExpress Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer.

Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer.

Tekniske data

Kemisk navn eller materiale Nevanimibe hydrochloride
CAS 133825-81-7
Farve White
Renhedsgrad noter Research
Molekylær formel C27H40ClN3O
Mængde 50 mg
Synonym PD-132301 hydrochloride ATR101 hydrochloride
Opløselighedsinformation DMSO : 41.67 mg/mL (90.97 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl
Molekylvægt (g/mol) 458.08
Formel vægt 458.08
Procent renhed 98.07%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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