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ML216, MedChemExpress

Artikelnummer. 16497827
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Artikelnummer. 16497827 Leverandør Medchem Express Leverandørnr. HY12342

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MedChemExpress ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 μM. Antitumor avtivity.

ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 μM. Antitumor avtivity.

Tekniske data

Kemisk navn eller materiale ML216
CAS 1430213-30-1
Farve Deep Yellow
Renhedsgrad noter Research
Molekylær formel C15H9F4N5OS
Mængde 5 mg
Synonym CID-49852229
Opløselighedsinformation DMSO : 20 mg/mL (52.18 mM; Need ultrasonic)
SMIL O=C(NC1=CC=C(F)C(C(F)(F)F)=C1)NC2=NN=C(S2)C3=CC=NC=C3
Molekylvægt (g/mol) 383.32
Formel vægt 383.32
Procent renhed 98.07%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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