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MK-886, MedChemExpress

Artikelnummer. 16453406
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Artikelnummer. Mængde
16453406 25 mg
16445978 10 mg
16438597 5 mg
16426406 100 mg
16402127 50 mg
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Artikelnummer. 16453406 Leverandør Medchem Express Leverandørnr. HY14166

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Beskrivelse

MedChemExpress MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.

MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.

Tekniske data

Kemisk navn eller materiale MK-886
CAS 118414-82-7
Farve White
Renhedsgrad noter Research
Molekylær formel C27H34ClNO2S
Mængde 25 mg
Synonym L 663536
Opløselighedsinformation DMSO : 75 mg/mL (158.87 mM; Need ultrasonic)
SMIL CC(C)C1=CC=C(N(CC2=CC=C(Cl)C=C2)C(CC(C)(C(O)=O)C)=C3SC(C)(C)C)C3=C1
Molekylvægt (g/mol) 472.08
Formel vægt 472.08
Procent renhed 99.11%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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