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LY2922470, MedChemExpress

Artikelnummer. 16477736
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16477736 100 mg
16467938 10 mg
16463877 50 mg
16400408 5 mg
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Artikelnummer. 16477736 Leverandør Medchem Express Leverandørnr. HY19835

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Beskrivelse

MedChemExpress LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40), with EC50s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1, is potential for the treatment of type 2 diabetes mellitus (T2DM).

LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40), with EC50s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1, is potential for the treatment of type 2 diabetes mellitus (T2DM).

Tekniske data

Kemisk navn eller materiale LY2922470
CAS 1423018-12-5
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C28H29NO4S
Mængde 100 mg
Opløselighedsinformation DMSO : ≥ 125 mg/mL (262.83 mM)
SMIL COC1=C(N(CC2=CC=C(COC3=CC=C([C@@H](C#CC)CC(O)=O)C=C3)S2)CCC4)C4=CC=C1
Molekylvægt (g/mol) 475.6
Formel vægt 475.6
Procent renhed 98.03%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-sugar/lipid metabolism
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Research purposes only

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