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KML29, MedChemExpress

Artikelnummer. 16487668
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16487668 10 mg
16483677 50 mg
16430138 5 mg
16407576 100 mg
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Artikelnummer. 16487668 Leverandør Medchem Express Leverandørnr. HY18977

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Beskrivelse

MedChemExpress KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.

KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.

Tekniske data

Kemisk navn eller materiale KML29
CAS 1380424-42-9
Farve White
Renhedsgrad noter Research
Molekylær formel C24H21F6NO7
Mængde 10 mg
Opløselighedsinformation DMSO : 50 mg/mL (91.01 mM; Need ultrasonic)
SMIL O=C(N1CCC(C(C2=CC=C(OCO3)C3=C2)(C4=CC=C(OCO5)C5=C4)O)CC1)OC(C(F)(F)F)C(F)(F)F
Molekylvægt (g/mol) 549.42
Formel vægt 549.42
Procent renhed 98.77%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-sugar/lipid metabolism
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Research purposes only

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