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  8. K145 hydrochloride, MedChemExpress

K145 hydrochloride, MedChemExpress

Artikelnummer. 16496936
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16496936 100 mg
16496828 10 mg
16439377 5 mg
16412907 50 mg
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Artikelnummer. 16496936 Leverandør Medchem Express Leverandørnr. HY15779A

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Beskrivelse

MedChemExpress K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.

K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.

Tekniske data

Kemisk navn eller materiale K145 hydrochloride
CAS 1449240-68-9
Farve White
Renhedsgrad noter Research
Molekylær formel C18H25ClN2O3S
Mængde 100 mg
Opløselighedsinformation H2O : 126.7 mg/mL (329.16 mM; Need ultrasonic and warming) ∣DMSO : 50 mg/mL (129.90 mM; Need ultrasonic)
SMIL O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl
Molekylvægt (g/mol) 384.92
Formel vægt 384.92
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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