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  8. IACS-010759 hydrochloride, MedChemExpress

IACS-010759 hydrochloride, MedChemExpress

Artikelnummer. 16495396
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10mg
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16495396 100 mg -
16474548 10 mg 10mg
16447267 5 mg -
16413126 25 mg -
16400857 50 mg -
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Artikelnummer. 16495396 Leverandør Medchem Express Leverandørnr. HY112037A

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Beskrivelse

MedChemExpress IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research.

IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research.

Tekniske data

Kemisk navn eller materiale IACS-010759 hydrochloride
CAS 1807523-99-4
Farve White
Renhedsgrad noter Research
Molekylær formel C25H26ClF3N6O4S
Mængde 100 mg
Synonym IACS-10759 hydrochloride
Opløselighedsinformation DMSO : 60 mg/mL (100.16 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL FC(F)(F)OC1=CC=C(C2=NOC(C3=NN(CC4=CC(N5CCC(S(=O)(C)=O)CC5)=CC=C4)C(C)=N3)=N2)C=C1.Cl
Molekylvægt (g/mol) 599.02
Formel vægt 599.02
Procent renhed 98.91%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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