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Gibco™ Human GM-CSF Recombinant Protein

Recombinant Protein

Brand: Gibco™ PHC2015

2242.00 DKK valid until 2025-05-31
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Product Code. 10797823

2485.00 DKK / Each

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Description

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water to 0.1-1.0 mg/mL to regain full activity. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in medium or buffered solution containing carrier protein, such as PBS with 0.1% BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Specifications

Accession Number	P04141
Formulation	protein with no preservative
Molecular Weight (g/mol)	14 kDa
Purification Method	Sequential Chromatography
Endotoxin Concentration	<0.1 ng/ μg
Common Name	GM-CSF
Conjugate	Unconjugated
Recombinant	Recombinant
Classification	Carrier-Free
Shipping Condition	Wet Ice
Protein Family	Cytokines & Receptors
Form	Lyophilized
Research Category	Signal Transduction, Oncology, Stem Cell Research, Differentiation, Drug Development
Purity or Quality Grade	>95% by SDS-PAGE

For Use With (Application)	Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
Gene ID (Entrez)	1437
Name	Human GM-CSF
Quantity	10 μg
Gene Alias	colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Biological Activity	ED50 < 0.1 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Species	Human
Content And Storage	4°C
Endotoxin Level	<0.1 ng/μg
Expression System	E. coli
Protein Form	Recombinant, Ligand
Protein Subtype	GM-CSF, G-CSF, & M-CSF
Product Line	Gibco™

Product Suggestions Documents

Documents

Product Information

Manuals

Product Sheet: Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (GM–CSF) Version: A.0 File size: 96.4 kB

Certificate of Origin_PHC2011, PHC2013, PHC2014, PHC2015 (Human GM-CSF) Version: 1.0 File size: 37.6 kB

Certificates

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Lot Number

5 results found

Lot Number	Certificate Type	Date	Catalog Number
Lot Number2449909	Certificate TypeCertificate of Analysis	Date31/01/2025	Catalog NumberPHC2015
Lot Number2558460	Certificate TypeCertificate of Analysis	Date29/01/2025	Catalog NumberPHC2015
Lot Number2678831	Certificate TypeCertificate of Analysis	Date29/01/2025	Catalog NumberPHC2015
Lot Number2907249	Certificate TypeCertificate of Analysis	Date26/01/2025	Catalog NumberPHC2015
Lot Number1503450B	Certificate TypeCertificate of Analysis	Date16/04/2017	Catalog NumberPHC2015

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Gibco™ Human GM-CSF Recombinant Protein > 10 μg; Unlabeled

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