missing translation for 'onlineSavingsMsg'
Learn More

Gibco™ Human GM-CSF Recombinant Protein

Recombinant Protein

Brand: Gibco™ PHC2013

View more versions of this product

Product Code. 10552045

37770.00 DKK / Each

Please sign in to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water to 0.1-1.0 mg/mL to regain full activity. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in medium or buffered solution containing carrier protein, such as PBS with 0.1% BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Specifications

Accession Number	P04141
Formulation	protein with no preservative
Molecular Weight (g/mol)	14 kDa
Purification Method	Sequential Chromatography
Endotoxin Concentration	<0.1 ng/ μg
Common Name	GM-CSF
Conjugate	Unconjugated
Recombinant	Recombinant
Classification	Carrier-Free
Shipping Condition	Wet Ice
Protein Family	Cytokines & Receptors
Form	Lyophilized
Research Category	Signal Transduction, Oncology, Stem Cell Research, Differentiation, Drug Development
Purity or Quality Grade	>95% by SDS-PAGE

For Use With (Application)	Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
Gene ID (Entrez)	1437
Name	Human GM-CSF
Quantity	1 mg
Gene Alias	colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Biological Activity	ED50 < 0.1 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Species	Human
Content And Storage	4°C
Endotoxin Level	<0.1 ng/μg
Expression System	E. coli
Protein Form	Recombinant, Ligand
Protein Subtype	GM-CSF, G-CSF, & M-CSF
Product Line	Gibco™

Product Suggestions Documents

Documents

Product Information

Manuals

Product Sheet: Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (GM–CSF) Version: A.0 File size: 96.4 kB

Certificate of Origin_PHC2011, PHC2013, PHC2014, PHC2015 (Human GM-CSF) Version: 1.0 File size: 37.6 kB

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

Lot Number

5 results found

Lot Number	Certificate Type	Date	Catalog Number
Lot Number2476205	Certificate TypeCertificate of Analysis	Date29/01/2025	Catalog NumberPHC2013
Lot Number2602266	Certificate TypeCertificate of Analysis	Date29/01/2025	Catalog NumberPHC2013
Lot Number2894748	Certificate TypeCertificate of Analysis	Date27/01/2025	Catalog NumberPHC2013
Lot Number1049417C	Certificate TypeCertificate of Analysis	Date18/07/2017	Catalog NumberPHC2013
Lot Number1364899C	Certificate TypeCertificate of Analysis	Date14/04/2017	Catalog NumberPHC2013

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

Gibco™ Human GM-CSF Recombinant Protein > 1 mg; Unlabeled

Your Name

Email Address *

Type of Issue *

Detailed Description of Issue/Request *

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

Spot an opportunity for improvement?Share a Content Correction