missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Rekombinante proteiner
  4. Gibco™ Human FGF-basic (FGF-2/bFGF) (aa 10-155) Recombinant Protein

Gibco™ Human FGF-basic (FGF-2/bFGF) (aa 10-155) Recombinant Protein

Artikelnummer. 10202733
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
1 mg
10 μg
100 μg
50 μg
Pakningsstørrelse:
100µg
50µg
Hver
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde unitSize
10202733 100 μg 100µg
10612074 1 mg Hver
10622074 10 μg Hver
10222253 50 μg 50µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 10202733 Leverandør Gibco™ Leverandørnr. PHG0021

Venligst for at købe denne vare. Brug for en webkonto? Register dig hos os i dag!

Edge
Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water to 0.1-0.5 mg/mL. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in medium or buffered solution containing carrier protein, such as PBS with 0.1% BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P09038
Til brug med (applikation) Bioactivity
Formulering Protein with no preservative
Gen-id (Entrez) 2247
Molekylvægt (g/mol) 17 kDa
Navn Human FGF-basic (FGF-2/bFGF) (aa 10-155)
Oprensningsmetode Purified
Mængde 100 μg
Opbevaringskrav 4°C
Regulatorisk status RUO
Endotoksin koncentration <0.1 ng/μg
Gene Alias Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); Fibroblast growth factor basic; HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
Fælles navn FGF2
Gen symbol FGF2
Biologisk aktivitet ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of BALB/3T3 cells.
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Sekvens Human FGF-basic, amino acids 10-155
Indhold og opbevaring 4°C
Aktivitet ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of BALB/3T3 cells.
Endotoksin niveau <0.1 ng/μg
Forsendelsestilstand Wet Ice
Udtrykssystem E. coli
Protein familie Growth Factors & Receptors
Protein form Recombinant, Ligand, Truncated
Form Lyophilized
Protein undertype FGFs (Fibroblast Growth Factors)
Forskningskategori Neurobiology, Oncology, Stem Cell Research, Microbiology, Differentiation, Angiogenesis
Produktlinje Gibco
Renhed eller kvalitetsklasse >95% by SDS-PAGE
Vis mere Vis mindre
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.