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GSK481, MedChemExpress

Artikelnummer. 16499476
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Artikelnummer. 16499476 Leverandør Medchem Express Leverandørnr. HY100131

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MedChemExpress GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.

GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.

Tekniske data

Kemisk navn eller materiale GSK481
CAS 1622849-58-4
Farve Brown
Renhedsgrad noter Research
Molekylær formel C21H19N3O4
Mængde 50 mg
Opløselighedsinformation DMSO : ≥ 35 mg/mL (92.74 mM)
SMIL O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
Molekylvægt (g/mol) 377.39
Formel vægt 377.39
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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