missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ GSK 583
Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable
614.00 DKK - 2275.00 DKK
Specifications
| Chemical Name or Material | 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
|---|---|
| CAS | 1346547-00-9 |
| Molecular Formula | C20H19FN4O2S |
| Purity | 98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18735636
|
Tocris Bioscience™
6480/5 |
5 mg |
614.00 DKK
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
18706046
|
Tocris Bioscience™
6480/25 |
25 mg |
2275.00 DKK
25mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent RIP2 kinase inhibitor (IC50 values are 2 and 5 nM at rat and human kinases, respectively). Displays selectivity for RIP2K over p38α, VEGFR2 and a panel of 300 kinases. Exhibits some inhibition at BRK and Aurora A. Also displays similar binding affinity, but no detectable functional activity at RIP3. Active in vivo. Moderately orally bioavailable and cell permeable.Specifications
| 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine | |
| 1346547-00-9 | |
| C20H19FN4O2S | |
| 98% |
Safety and Handling
Recommended Storage : Store at -20°C
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Tocris Bioscience™ GSK 583