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Glibenclamide, MedChemExpress

Artikelnummer. 16431489
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1 g
5 g
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16431489 1 g
16448957 5 g
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Artikelnummer. 16431489 Leverandør Medchem Express Leverandørnr. HY15206
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Forventet forsendelse: 31-07-2026
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Description

MedChemExpress Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity.

Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.

Specifications

Kemisk navn eller materiale Glibenclamide
CAS 10238-21-8
Farve White
Renhedsgrad noter Research
Molekylær formel C23H28ClN3O5S
Mængde 1 g
Synonym Glyburide
Opløselighedsinformation DMSO : 250 mg/mL (506.07 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.20 mM; Need ultrasonic and warming)
SMIL ClC1=CC(C(NCCC2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)=O)=C(OC)C=C1
Molekylvægt (g/mol) 494.0
Formel vægt 494.0
Procent renhed 98.89%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-protein/nucleotide metabolism
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Research purposes only

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