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Geldanamycin, 98+%, Thermo Scientific™
Benzoquinoid antibiotic that inhibits pp60src tyrosine kinase
Ring for pris
Kemiske identifikatorer
| CAS | 30562-34-6 |
|---|---|
| Molekylær formel | C29H40N2O9 |
| Molekylvægt (g/mol) | 560.644 |
| MDL nummer | MFCD00274570 |
| InChI nøgle | QTQAWLPCGQOSGP-KDFVLELPSA-N |
| Synonym | NSC 122750; U-29135 |
| PubChem CID | 133688416 |
| IUPAC navn | [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate |
| SMIL | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC |
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|
15405649
|
Thermo Scientific Alfa Aesar
J63397.MB |
25mg |
Ring for pris
25mg |
Ikke relevant | Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | ||||
|
15415649
|
Thermo Scientific Alfa Aesar
J63397.MC |
100mg |
Ring for pris
100mg |
Ikke relevant | Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | ||||
|
15425649
|
Thermo Scientific Alfa Aesar
J63397.MD |
250mg |
Ring for pris
250mg |
Ikke relevant | Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | ||||
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsGeldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
Solubility
Soluble in dimethyl sulfoxide at 100 mg/mL.
Notes
Store in a cool dry place. Keep away from oxidizing agents. Protect from heat.
Kemiske identifikatorer
| 30562-34-6 | |
| 560.644 | |
| QTQAWLPCGQOSGP-KDFVLELPSA-N | |
| 133688416 | |
| CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC |
| C29H40N2O9 | |
| MFCD00274570 | |
| NSC 122750; U-29135 | |
| [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate |
Tekniske data
| Geldanamycin | |
| Yellow to Orange | |
| MFCD00274570 | |
| Soluble in dimethyl sulfoxide at 100mg/mL. | |
| CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC | |
| 560.644 | |
| 560.64 |
| 30562-34-6 | |
| C29H40N2O9 | |
| NSC 122750; U-29135 | |
| QTQAWLPCGQOSGP-KDFVLELPSA-N | |
| [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | |
| 133688416 | |
| ≥99% |
Sikkerhed og håndtering
missing translation for 'rtecsNumber' : LX8920000
missing translation for 'tsca' : No
Anbefalet opbevaring : Store at -20°C
RUO – Research Use Only
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