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Gefitinib, MedChemExpress

Artikelnummer. 16491926
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Artikelnummer. Mængde
16491926 500 mg
16487886 100 mg
16431949 1 g
16480588 5 g
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Artikelnummer. 16491926 Leverandør Medchem Express Leverandørnr. HY50895

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Beskrivelse

MedChemExpress Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Tekniske data

Kemisk navn eller materiale Gefitinib
CAS 184475-35-2
Farve White
Renhedsgrad noter Research
Molekylær formel C22H24ClFN4O3
Mængde 500 mg
Synonym ZD1839
Opløselighedsinformation DMSO : 125 mg/mL (279.70 mM; Need ultrasonic)
SMIL ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F
Molekylvægt (g/mol) 446.9
Formel vægt 446.9
Procent renhed 95.0%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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