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FT113, MedChemExpress

Artikelnummer. 16494488
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Artikelnummer. Mængde
16494488 10 mg
16417217 5 mg
16410807 50 mg
16405366 100 mg
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Artikelnummer. 16494488 Leverandør Medchem Express Leverandørnr. HY111551

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Beskrivelse

MedChemExpress FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo.

FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo.

Tekniske data

Kemisk navn eller materiale FT113
CAS 1630808-89-7
Farve White
Renhedsgrad noter Research
Molekylær formel C22H20FN3O4
Mængde 10 mg
Opløselighedsinformation DMSO : 62.5 mg/mL (152.66 mM; Need ultrasonic)
SMIL O=C(C1(CC1)O)N2CCN(C(C3=CC=C(C4=NC5=C(C=C(F)C=C5)O4)C=C3)=O)CC2
Molekylvægt (g/mol) 409.41
Formel vægt 409.41
Procent renhed 99.61%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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