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DL-Thioctic acid, 98%, Thermo Scientific™

DL-Thioctic acid, CAS # 1077-28-7, is an antioxidant and coenzyme important for the activity of enzymes.

507.65 DKK - 1638.65 DKK

Kemiske identifikatorer

CAS 1077-28-7
Molekylær formel C8H14O2S2
Molekylvægt (g/mol) 206.32
MDL nummer MFCD00005474
InChI nøgle AGBQKNBQESQNJD-UHFFFAOYNA-N
Synonym dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid
PubChem CID 864
ChEBI CHEBI:16494
IUPAC navn 5-(1,2-dithiolan-3-yl)pentanoic acid
SMIL OC(=O)CCCCC1CCSS1
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Produkter 2
Produktkode Brand Mængde Pris Antal & tilgængelighed  
Produktkode Brand Mængde Pris Antal & tilgængelighed  
11321687
Dokumentvisning
Thermo Scientific Alfa Aesar
L04711.06
5g
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564.19 DKK
507.65 DKK / 5g
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10% Slukket
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11409820
Dokumentvisning
Thermo Scientific Alfa Aesar
L04711.14
25g
ONLINE EXCLUSIVE PRICE
1820.92 DKK
1638.65 DKK / 25g
Spare 182.27 DKK
10% Slukket
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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• DL-Thioctic acid derives from octanoic acid, and it has been described as an antioxidant coenzyme important for the activity of enzyme complexes including pyruvate dehydrogenase and glycine decarboxylase

Application

• DL-Thioctic acid has been used in in vivo studies to increase insulin sensitivity and stimulate glucose uptake into adipose and muscle cells in vitro

• DL-Thioctic acid has an essential role in aerobic metabolism

• It has been used as free radical scavenger compound

• It can also assist in repairing oxidative damage via the increase of endogenous antioxidants, including vitamins C, vitamin E, and glutathione

• It can induce apoptosis through caspase-independent and caspase-dependent pathways, a process mediated by intracellular Ca2+

• DL-Thioctic acid has the ability to impact various cellular biological pathways since it can increase glutathione synthesis and modulate transcription factor activity, mainly nuclear factor kappa B (NF-κB)

• It can decrease the phagocytosis of myelin by macrophages

Tekniske data

Kemiske identifikatorer

1077-28-7
206.32
AGBQKNBQESQNJD-UHFFFAOYNA-N
864
5-(1,2-dithiolan-3-yl)pentanoic acid
C8H14O2S2
MFCD00005474
dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid
CHEBI:16494
OC(=O)CCCCC1CCSS1

Especificaciones

DL-Thioctic acid
160°C to 165°C
MFCD00005474
14,9326
Soluble in methanol,ethanol,diethyl ether and chloroform. Insoluble in water.
OC(=O)CCCCC1CCSS1
206.32
CHEBI:16494
98%
1077-28-7
C8H14O2S2
81853
dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid
AGBQKNBQESQNJD-UHFFFAOYNA-N
5-(1,2-dithiolan-3-yl)pentanoic acid
864
206.33
Videos
Seguridad y manipulación

Seguridad y manipulación

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

missing translation for 'einecsNumber' : 214-071-2

missing translation for 'rtecsNumber' : JP1192000

missing translation for 'tsca' : No

Recommended Storage : Keep cold

Nombre del producto
  • DL-Thioctic acid

Palabra de advertencia
  • Advarsel

Clasificación
  • Akut toksicitet Kategori 4
  • Alvorlige øjenskader/øjenirritation Kategori 2
  • Hudætsning/hudirritation Kategori 2
  • Specifik målorgantoksicitet - enkelt eksponering Kategori 2

Indicaciones de peligro
  • H302-Farlig ved indtagelse.
  • H315-Forårsager hudirritation.
  • H319-Forårsager alvorlig øjenirritation.
  • H335-Kan forårsage irritation af luftvejene.

Consejos de prudencia
  • P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
  • P301+P330+P331-I TILFÆLDE AF INDTAGELSE: Skyl munden. Fremkald IKKE opkastning.
  • P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
  • P304+P340-VED INDÅNDING: Flyt personen til et sted med frisk luft og sørg for, at vejrtrækningen lettes.
  • P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .
  • P332+P313-Ved hudirritation: Søg lægehjælp.
  • P337+P313-Ved vedvarende øjenirritation: Søg lægehjælp.

Otros peligros
  • MIXTURE LIST-Contain: DL-Thioctic acid

SDS
Documentos

Documentos

Product Certifications

RUO – Research Use Only

Título del producto
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