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DL-Thioctic acid, 98%, Thermo Scientific™
DL-Thioctic acid, CAS # 1077-28-7, is an antioxidant and coenzyme important for the activity of enzymes.
507.65 DKK - 1638.65 DKK
Kemiske identifikatorer
| CAS | 1077-28-7 |
|---|---|
| Molekylær formel | C8H14O2S2 |
| Molekylvægt (g/mol) | 206.32 |
| MDL nummer | MFCD00005474 |
| InChI nøgle | AGBQKNBQESQNJD-UHFFFAOYNA-N |
| Synonym | dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid |
| PubChem CID | 864 |
| ChEBI | CHEBI:16494 |
| IUPAC navn | 5-(1,2-dithiolan-3-yl)pentanoic acid |
| SMIL | OC(=O)CCCCC1CCSS1 |
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|
11321687
|
Thermo Scientific Alfa Aesar
L04711.06 |
5g |
564.19 DKK 507.65 DKK / 5g Spare 56.54 DKK 10% Slukket |
Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | |||||
|
11409820
|
Thermo Scientific Alfa Aesar
L04711.14 |
25g |
1820.92 DKK 1638.65 DKK / 25g Spare 182.27 DKK 10% Slukket |
Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | |||||
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• DL-Thioctic acid derives from octanoic acid, and it has been described as an antioxidant coenzyme important for the activity of enzyme complexes including pyruvate dehydrogenase and glycine decarboxylase
Application
• DL-Thioctic acid has been used in in vivo studies to increase insulin sensitivity and stimulate glucose uptake into adipose and muscle cells in vitro
• DL-Thioctic acid has an essential role in aerobic metabolism
• It has been used as free radical scavenger compound
• It can also assist in repairing oxidative damage via the increase of endogenous antioxidants, including vitamins C, vitamin E, and glutathione
• It can induce apoptosis through caspase-independent and caspase-dependent pathways, a process mediated by intracellular Ca2+
• DL-Thioctic acid has the ability to impact various cellular biological pathways since it can increase glutathione synthesis and modulate transcription factor activity, mainly nuclear factor kappa B (NF-κB)
• It can decrease the phagocytosis of myelin by macrophages
Kemiske identifikatorer
| C8H14O2S2 | |
| MFCD00005474 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| CHEBI:16494 | |
| OC(=O)CCCCC1CCSS1 |
Especificaciones
| DL-Thioctic acid | |
| 160°C to 165°C | |
| MFCD00005474 | |
| 14,9326 | |
| Soluble in methanol,ethanol,diethyl ether and chloroform. Insoluble in water. | |
| OC(=O)CCCCC1CCSS1 | |
| 206.32 | |
| CHEBI:16494 | |
| 98% |
| 1077-28-7 | |
| C8H14O2S2 | |
| 81853 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| AGBQKNBQESQNJD-UHFFFAOYNA-N | |
| 5-(1,2-dithiolan-3-yl)pentanoic acid | |
| 864 | |
| 206.33 |
Seguridad y manipulación
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
missing translation for 'einecsNumber' : 214-071-2
missing translation for 'rtecsNumber' : JP1192000
missing translation for 'tsca' : No
Recommended Storage : Keep cold
- DL-Thioctic acid
Palabra de advertencia
- Advarsel
Clasificación
- Akut toksicitet Kategori 4
- Alvorlige øjenskader/øjenirritation Kategori 2
- Hudætsning/hudirritation Kategori 2
- Specifik målorgantoksicitet - enkelt eksponering Kategori 2
Indicaciones de peligro
- H302-Farlig ved indtagelse.
- H315-Forårsager hudirritation.
- H319-Forårsager alvorlig øjenirritation.
- H335-Kan forårsage irritation af luftvejene.
Consejos de prudencia
- P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
- P301+P330+P331-I TILFÆLDE AF INDTAGELSE: Skyl munden. Fremkald IKKE opkastning.
- P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
- P304+P340-VED INDÅNDING: Flyt personen til et sted med frisk luft og sørg for, at vejrtrækningen lettes.
- P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .
- P332+P313-Ved hudirritation: Søg lægehjælp.
- P337+P313-Ved vedvarende øjenirritation: Søg lægehjælp.
Otros peligros
- MIXTURE LIST-Contain: DL-Thioctic acid
RUO – Research Use Only
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