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CEP-28122 mesylate salt, MedChemExpress

Artikelnummer. 16453477
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Artikelnummer. 16453477 Leverandør Medchem Express Leverandørnr. HY18030A
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Forventet forsendelse: 20-11-2026
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Description

MedChemExpress CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

Specifications

Kemisk navn eller materiale CEP-28122 mesylate salt
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C29H39ClN6O6S
Mængde 50 mg
Opløselighedsinformation DMSO : ≥ 6.4 mg/mL (10.08 mM)
SMIL O=C([C@H]1[C@](C2)([H])C=C[C@]2([H])[C@H]1NC3=NC(NC4=CC=C5C(CC[C@@H](N6CCOCC6)CC5)=C4OC)=NC=C3Cl)N.O=S(C)(O)=O
Molekylvægt (g/mol) 635.17
Formel vægt 635.17
Procent renhed 99.85%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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