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CDKI-73, MedChemExpress

Artikelnummer. 16485168
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Artikelnummer. Mængde
16485168 10 mg
16421397 50 mg
16417897 5 mg
16405876 100 mg
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Artikelnummer. 16485168 Leverandør Medchem Express Leverandørnr. HY12445

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Beskrivelse

MedChemExpress CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. CDKI-73 down-regulates the RNAPII phosphorylation. CDKI-73 is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion.

CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. CDKI-73 down-regulates the RNAPII phosphorylation. CDKI-73 is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion.

Tekniske data

Kemisk navn eller materiale CDKI-73
CAS 1421693-22-2
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C15H15FN6O2S2
Mængde 10 mg
Synonym LS-007
Opløselighedsinformation DMSO : ≥ 52 mg/mL (131.83 mM)
SMIL CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1
Molekylvægt (g/mol) 394.45
Formel vægt 394.45
Procent renhed 98.36%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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