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CD223 (LAG-3) Monoclonal Antibody (3DS223H), Super Bright™ 645, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

2985.00 DKK

Specifications

Antigen CD223 (LAG-3)
Clone 3DS223H
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15933644
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Affymetrix eBioscience
64-2239-42
100 Tests
2985.00 DKK
Pack of 100
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Estimated Shipment: 11-04-2024
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Description

Description

Description: The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predomitly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969). Applications Reported: This eBioJ105 (J105) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioJ105 (J105) antibody has been pre-titrated and tested by flow cytometic analysis of PHA stimulated human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 645 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 645 nm. We recommend using a 660/20 bandpass filter.

CD223 (LAG-3) Monoclonal antibody specifically detects CD223 (LAG-3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD223 (LAG-3)
5 μL/Test
Monoclonal
Liquid
RUO
P18627
LAG3
Primary
4° C, store in dark, DO NOT FREEZE!
LAG3
3DS223H
Flow Cytometry
Super Bright 645
Mouse
Human
3902
IgG1 κ
Affinity chromatography
Antibody
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