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C188-9, MedChemExpress Product Code.: 16475456
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C188-9, MedChemExpress

Product Code. 16475456
100 mg, 100mg
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Product Code. 16475456

Brand: Medchem Express HY112288

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Description

MedChemExpress C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts.

C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts.

Specifications

Chemical Name or Material C188-9
CAS 432001-19-9
Color Pink
Purity Grade Notes Research
Molecular Formula C27H21NO5S
Quantity 100 mg
Synonym TTI-101
Solubility Information DMSO : 25 mg/mL (53.02 mM; ultrasonic and warming and heat to 60°C)
SMILES O=S(C1=CC=C(OC)C=C1)(NC2=C3C=CC=CC3=C(O)C(C4=C5C=CC=CC5=CC=C4O)=C2)=O
Molecular Weight (g/mol) 471.52
Formula Weight 471.52
Percent Purity 98.11%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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