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Brexpiprazole, MedChemExpress

Artikelnummer. 16406838
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16406838 10 mg
16471786 500 mg
16449377 5 mg
16422907 50 mg
16411206 200 mg
16406946 100 mg
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Artikelnummer. 16406838 Leverandør Medchem Express Leverandørnr. HY15780

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Beskrivelse

MedChemExpress Brexpiprazole (OPC-34712), an atypical orally active antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM).

Brexpiprazole (OPC-34712), an atypical orally active antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM).

Tekniske data

Kemisk navn eller materiale Brexpiprazole
CAS 913611-97-9
Farve White
Renhedsgrad noter Research
Molekylær formel C25H27N3O2S
Mængde 10 mg
Synonym OPC-34712
Opløselighedsinformation DMSO : 25 mg/mL (57.66 mM; ultrasonic and warming and heat to 80°C)
SMIL O=C1NC2=C(C=CC(OCCCCN3CCN(C4=C(C=CS5)C5=CC=C4)CC3)=C2)C=C1
Molekylvægt (g/mol) 433.57
Formel vægt 433.57
Procent renhed 98.25%
Grad Research
Fysisk form Powder
Til brug med (applikation) Neuroscience-Neuromodulation
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Research purposes only

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