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AX-024 hydrochloride, MedChemExpress

Artikelnummer. 16492956
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Mængde:
2 mg
5 mg
10 mg
25 mg
50 mg
100 mg
Pakningsstørrelse:
25mg
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16492956 25 mg 25mg
16480477 50 mg -
16416827 5 mg -
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Artikelnummer. 16492956 Leverandør Medchem Express Leverandørnr. HY107390A

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Beskrivelse

MedChemExpress AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

Tekniske data

Kemisk navn eller materiale AX-024 hydrochloride
CAS 1704801-24-0
Farve White
Renhedsgrad noter Research
Molekylær formel C21H23ClFNO2
Mængde 25 mg
Opløselighedsinformation DMSO : 33 mg/mL (87.80 mM; Need ultrasonic and warming) ∣H2O : 16.67 mg/mL (44.35 mM; Need ultrasonic)
SMIL COC1=CC=C(OC2)C(C(C3=CC=C(F)C=C3)=C2CN4CCCC4)=C1.[H]Cl
Molekylvægt (g/mol) 375.86
Formel vægt 375.86
Procent renhed 99.12%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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