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Autophinib, MedChemExpress

Artikelnummer. 16486367
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16486367 5 mg 5mg
16480066 2 mg -
16463638 10 mg -
16424726 100 mg -
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Artikelnummer. 16486367 Leverandør Medchem Express Leverandørnr. HY101920

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Beskrivelse

MedChemExpress Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.

Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.

Tekniske data

Kemisk navn eller materiale Autophinib
CAS 1644443-47-9
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C14H11ClN6O3
Mængde 5 mg
Opløselighedsinformation DMSO : ≥ 30 mg/mL (86.52 mM)
SMIL CC1=CC(NC2=NC(OC3=CC=C([N+]([O-])=O)C=C3)=NC(Cl)=C2)=NN1
Molekylvægt (g/mol) 346.73
Formel vægt 346.73
Procent renhed 99.56%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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