missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Kemikalier
  4. Organiske forbindelser
  5. Benzenoider
  6. Benzen og substituerede derivater
  7. Fluorbenzener
  8. Adezmapimod hydrochloride, MedChemExpress

Adezmapimod hydrochloride, MedChemExpress

Artikelnummer. 16484806
Encompass_Preferred
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
10 mg
50 mg
100 mg
200 mg
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde
16484806 100 mg
16450127 50 mg
16423748 10 mg
16410966 200 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 16484806 Leverandør Medchem Express Leverandørnr. HY10256A

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

MedChemExpress Adezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride is an autophagy and mitophagy activator.

Adezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride is an autophagy and mitophagy activator.

Tekniske data

Kemisk navn eller materiale Adezmapimod hydrochloride
CAS 869185-85-3
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C21H17ClFN3OS
Mængde 100 mg
Synonym SB 203580 hydrochlorideRWJ 64809 hydrochloride
Opløselighedsinformation DMSO : 100 mg/mL (241.60 mM; Need ultrasonic) ∣H2O : 8.43 mg/mL (20.37 mM; Need ultrasonic and warming)
SMIL O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C.[H]Cl
Molekylvægt (g/mol) 413.9
Formel vægt 413.9
Procent renhed 98.6%
Grad Research
Fysisk form Powder
Til brug med (applikation) COVID-19-immunoregulation
Vis mere Vis mindre

Research purposes only

Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.