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ABBV-744, MedChemExpress

Artikelnummer. 16467277
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Artikelnummer. Mængde
16467277 5 mg
16450867 50 mg
16424568 10 mg
16403136 25 mg
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Artikelnummer. 16467277 Leverandør Medchem Express Leverandørnr. HY112090

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Beskrivelse

MedChemExpress ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

Tekniske data

Kemisk navn eller materiale ABBV-744
CAS 2138861-99-9
Farve White
Renhedsgrad noter Research
Molekylær formel C28H30FN3O4
Mængde 5 mg
Opløselighedsinformation DMSO : 100 mg/mL (203.44 mM; Need ultrasonic)
SMIL CC(O)(C)C1=CC(C(C2=C3NC(C(NCC)=O)=C2)=CN(C)C3=O)=C(OC4=C(C)C=C(F)C=C4C)C=C1
Molekylvægt (g/mol) 491.55
Formel vægt 491.55
Procent renhed 98.22%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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