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CAS RN 219911-35-0

CAS RN 219911-35-0

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1

Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Target Group I mGluR Antagonists
CAS 219911-35-0
Solubility Soluble to 100mM in DMSO
Purity 99%
Chemical Name or Material 2-Methyl-6-(phenylethynyl)pyridine hydrochloride
Recommended Storage Desiccate at +4°C
Molecular Formula C14H11N.HCl
Formula Weight Observed MW: 229.71
Assay Percent Range >99%
2

Medchem Express MPEP Hydrochloride, MedChemExpress

MedChemExpress MPEP Hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 229.7
Color White
Physical Form Solid
Chemical Name or Material MPEP Hydrochloride
Grade Research
SMILES CC1=NC(C#CC2=CC=CC=C2)=CC=C1.[H]Cl
For Use With (Application) Neuroscience-Neurodegeneration
Percent Purity 99.69%
CAS 219911-35-0
Solubility Information H2O : ≥ 50 mg/mL (217.68 mM)
Health Hazard 1 H302
Purity Grade Notes Research
Recommended Storage 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula C14H12ClN
Formula Weight 229.7
3

Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

ENCOMPASS
4

Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

ENCOMPASS

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