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Tocris Bioscience™ MPEP hydrochloride
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Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Brand:  Tocris Bioscience™ 1212/50

Encompass

Product Code. 13448893

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Description

Description

MPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
Specifications

Specifications

2-Methyl-6-(phenylethynyl)pyridine hydrochloride
>99%
Soluble to 100mM in DMSO
219911-35-0
50 mg
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