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MedChemExpress Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, respectively.
Molecular Weight (g/mol) | 602.7 |
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Color | Light Yellow |
Physical Form | Solid |
Chemical Name or Material | Abemaciclib methanesulfonate |
Grade | Research |
SMILES | CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C.CS(=O)(O)=O |
For Use With (Application) | Cancer-Kinase/protease |
Percent Purity | 98.0% |
CAS | 1231930-82-7 |
Solubility Information | H2O : 125 mg/mL (207.40 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (16.59 mM; ultrasonic and warming and heat to 80°C) |
Health Hazard 1 | H360∣H373∣H410 |
Synonym | LY2835219 methanesulfonate |
Purity Grade Notes | Research |
Recommended Storage | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
Shelf Life | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
Molecular Formula | C28H36F2N8O3S |
Formula Weight | 602.7 |