CAS RN 944396-07-0

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NVP-BKM 120, TRC

CAS: 944396-07-0 Molekylær formel: C18H21F3N6O2 Molekylvægt (g/mol): 410.39 Synonym: BKM 120,5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine,NVP-BKM 120 IUPAC navn: 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine SMIL: Nc1cc(c(cn1)c2cc(nc(n2)N3CCOCC3)N4CCOCC4)C(F)(F)F

Pris og tilgængelighed
Tekniske data

Molekylvægt (g/mol)	410.39
CAS	944396-07-0
Synonym	BKM 120,5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine,NVP-BKM 120
SMIL	Nc1cc(c(cn1)c2cc(nc(n2)N3CCOCC3)N4CCOCC4)C(F)(F)F
IUPAC navn	5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
Molekylær formel	C18H21F3N6O2

Buparlisib, MedChemExpress

MedChemExpress Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Buparlisib
Formel vægt	410.39
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (243.67 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	99.12%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	410.39
CAS	944396-07-0
Synonym	BKM120 NVP-BKM120
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	FC(F)(C1=C(C2=CC(N3CCOCC3)=NC(N4CCOCC4)=N2)C=NC(N)=C1)F
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₂₁F₃N₆O₂
Til brug med (applikation)	Cancer-Kinase/protease

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