CAS RN 936623-90-4

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Sacubitril/Valsartan, MedChemExpress

MedChemExpress Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Sacubitril/Valsartan
Formel vægt	957.99
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (104.39 mM) ∣H2O : ≥ 50 mg/mL (52.19 mM)
Procent renhed	99.0%
Fysisk form	Powder
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	957.99
CAS	936623-90-4
Synonym	LCZ696
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C(CCC(O[Na])=O)N([C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O)[H].O=C(O[Na])[C@@H](N(C(CCCC)=O)CC3=CC=C(C4=CC=CC=C4C5=NN=NN5[Na])C=C3)C(C)C.[2.5H2O]
Renhedsgrad noter	Research
Molekylær formel	C₄₈H₅₅N₆Na₃O₈.₂.₅H₂O
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 936623-90-4

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